EVALUATION OF SYNERGISTIC ANTIULCER ACTIVITY OF AEGLE MARMELOS AND OCIMUM SANCTUM IN ULCER INDUCED WISTAR RATS

Laxmikant Tyagi, Neha Sharma, Dr. Anuj Sharma, Dr. Shamim Ahmad

Abstract


This study has showed that the potential of treating ulcer by herbal drugs is effective as the synthetic drugs. On other hand, Synthetic drugs have many adverse effects on patient health and are target oriented while the herbal drugs have potential of treating ulcer and also have positive effect on curing other diseases (diabetes, arthritis, CV diseases etc that have been proved by many researches) with minimal adverse effects. So Ethanolic extracts of AM and OS in combination has the therapeutic potential to control gastric ulcer. However further studies are required to established its exact mode of action and active.

Key Words: Antiulcer, Aegle Marmelos, Ocimum Sanctum


Full Text:

PDF

References


Bharat BhusanMohapatra, Anti-Ulcer Activity Of Aqueous And Ethanolic Leaf Extract Of Krishna Tulasi(Ocimum Sanctum) In Albino Rats, April – June 2013, RJPBCS, Volume 4 Issue 2 Page No. 961-967

ThabrewMi, An Overview Of In Vivo And In Vitro Models That Can Be Used For Evaluating Anti-Gastric Ulcer Potential Of Medicinal Plants. Austin Biol- Volume 1 Issue 2 - 2016

TripathiKd. Essentials Of Medical Pharmacology. 6th Ed. Medical Publishers (P) Ltd: New Delhi, India: 2008.

Mathew Georg, Phytochemical And Pharmacological Screening Of In Vivo Anti-Inflammatory Activity Of AegleMarmelos(L.) Corr. Serr.Journal of Chemical and Pharmaceutical Research, 2016, 8(2):330-334

Asaduzzaman M, Phytochemicals, Nutritonal Constituents, Anti-Bacterial and Hypoglycemic Activity OfAegleMarmelos Lin. Leaf Extract In Alloxan Induced Diabetic Rats. Journal for nutrition and food sciences, 2016, 6:4

Sachin Kumar, Antioxidant Activity Of Leaf Extract Of AegleMarmelosCorrea ExRoxb.Pharmacogn. J. 2016;8(5):447-450

Khanna P, Cardioprotective Activity Of Methanolic Extract Of AegleMarmelos Leaf Extract Against Isoproterenol Induced Myocardial Damage In Rats. Journal of Pharmaceutical Research Vol. 9, No. 1, January 2010: 35-38.

NeelamBalekar, Evaluation Of Antiulcer Activity Of Whole Plant Extract Of MalvastrumTricuspidatum In Experimental Animals. Iranian Journal Of Pharmacology & Therapeutics 11: 53-59, 2012

MastewalAbebaw, Evaluation of Anti-Ulcer Activity Of The Leaf Extract Of OsyrisQuadripartitaDecne. (Santalaceae) In Rats

Available at-https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5248980/table/t1-jep-9-001

Shay, H., Sun, D. C. H., Gruenstein, M. 1954. A Quantitative Method For Measuring Spontaneous Gastric Secretion In The Rat. Gastroenterol, 26: 906-913

Prabhu K and Rajan S, Assessment Of Antiulcer Activity Of Ethanolic Extract Of MangiferaIndica Seed Kernel Using Acid Ethanol Induced Ulcer Model. Int.J.Curr.Microbiol.App.Sci (2015) 4(4): 854-860

S. Sharmila, Gastro Protective Effect Of Aqueous Extracts Of AegleMarmelos Unripe Fruit In Albino Rats, International Journal of Medicine and Pharmaceutical Sciences (IJASR) ISSN 2250-0049 Vol. 3, Issue 1, Mar 2013, 21-26

T. Satyanarayanaa, P. Dwarakanadha Reddy, Evaluation Of Anti-ulcer Activity By Poly Herbal Formulation On Indomethacin Induced Gastric Ulcers. Int. J. Chem. Sci.: 8(3), 2010, 1537-1544

Raju.D, Evaluation of Anti-Ulcer Activity of Methanolic Extract Of TerminaliaChebula Fruits In Experimental Rats. Journal for Pharm. Sciences & Res. Vol.1(3), 2009, 101‐107.

Ashoka M. Shenoy, Evaluation Of Anti-ulcer Activity Of Aegle Marmelos Leaves Extract, IJPSR (2012), Vol. 3, Issue 05): 1498-1501


Refbacks

  • There are currently no refbacks.