MEDOVAHA SROTODUSHTI IN NON-ALCOHOLIC FATTY LIVER DISEASE: AN INTEGRATED AYURVEDIC AND CONTEMPORARY PERSPECTIVE

Abstract

Non-alcoholic fatty liver disease (NAFLD), recently reclassified as Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD). This condition represents a significant global health burden with an estimated prevalence of 25-32% worldwide. This comprehensive review explores the Ayurvedic concept of Medovaha Srotodushti (vitiation of channels carrying adipose tissue) and its relationship to NAFLD pathogenesis. Through systematic analysis of classical Ayurvedic texts and contemporary scientific literature, the etiological factors, pathophysiological mechanisms, clinical manifestations and management strategies that connect these two diagnostic paradigms were examined. The review highlights that dietary indiscretions, sedentary lifestyle genetic predispositions contribute to both Medovaha Srotodushti and NAFLD through similar metabolic pathways. Ayurvedic management emphasizes shodhana chikitsa (purification therapies), medohara dravya (fat-reducing substances), and pathya-apathya (dietary and lifestyle modifications) which show promising results in clinical applications. Integration of Ayurvedic principles with modern medical approaches offers a comprehensive framework for addressing the multifactorial nature of NAFLD, potentially leading to more effective prevention and treatment strategies. This synthesis of traditional wisdom and contemporary science provides valuable insights for clinicians and researchers seeking holistic approaches to metabolic liver disorders.