RED BLOOD CELL INDICES VARIATIONS IN SICKLE CELL ANEMIA W.S.R. TO PANDU

Abstract

The presence of sickle hemoglobin (Hb S) in red blood cells causes sickle cell disease (SCD), one of the most significant and common hemoglobinopathies. When red blood cells are exposed to low oxygen tension, sickling occurs. It is usually autosomal recessive, meaning that a person inherits it from their parents. This disease is characterised by chronic Haemolytic Anaemia. Changes in Red Blood Cells can be observed and interpreted from a well furnished report of Red Blood Cell Indices. Red Blood Cell indices include PCV, MCV, MCH, MCHC and RDW. Ayurveda texts has not explained Sickle Cell Disease directly, rather explained it as Pandu Rog with the symptoms like Raktalpta (low Haemoglobin), Aruchi (Anorexia), Daurbalya (debility), Shwas (Dyspnoea), Jwar (Fever), Shoola (Pain) etc. It can be correlated with Sickle Cell Anemia due to the fact that many of the symptoms that are mentioned in Pandu Rog are similar to the symptoms mentioned in sickle cell disease. Further in this Article variations of Red blood cells Indices in Sickle Cell Anaemia w.s.r to Pandu will be highlighted.