LONG-STANDING GENERALIZED CUTANEOUS AMYLOIDOSIS AT DR BATRA’S

Abstract

Background

Primary localized cutaneous amyloidosis (PLCA) is a chronic dermatological disorder characterized by deposition of amyloid within the skin. Macular and lichen amyloidosis are the common non-nodular forms. Clinical presentation varies, with pigmentation and textural changes being prominent features. (PubMed)

Case Presentation

A patient with a history of brownish, dry cutaneous eruptions since the age of 12 years, clinically reported as amyloidosis, presented with increased lesions over the preceding four months. Lesions were reported over the hands, palms, chest, back and legs and were not associated with itching. The patient also had allergic sinusitis for 4–5 years, aggravated by changes in temperature/weather, strong smells, dust and perfumes. The patient reported a hot thermal state, disturbed sleep, low water intake, reduced physical activity and weight gain. A significant emotional component was described following financial loss in the share market, with anxiety developing easily. Family history included depression in the father, grandfather and uncle.

The patient had not taken treatment specifically for the skin condition. During longitudinal follow-up, the condition was subsequently documented as stable and, at the latest follow-up on 10 August 2026, as better. The documented prescription at that visit was Petroleum 200C and Kali sulphuricum 6X.

Conclusion

This case describes a chronic, long-standing cutaneous disorder clinically reported as amyloidosis with recent generalized exacerbation and subsequent documentation of clinical improvement during longitudinal follow-up. However, because histopathology and Congo-red confirmation are not provided in the available record, the subtype and pathological diagnosis cannot be independently confirmed from the supplied data. The case therefore represents a clinically diagnosed/reportedly diagnosed cutaneous amyloidosis case, rather than a biopsy-confirmed case.