THE INTERRELATIONSHIP OF VATA DOSHA, ASTHI DHATU, AND ASTHIVAHA SROTAS IN THE PATHOGENESIS OF ASTHIPRADOSHAJA VIKARA
DOI:
https://doi.org/10.5281/zenodo.21942527Keywords:
Vata Dosha; Asthi Dhatu; Asthivaha Srotas; Asthipradoshaja Vikara; Asthi Kshaya; SampraptiAbstract
Background: Ayurveda describes skeletal health through the interdependent concepts of Vata Dosha, Asthi Dhatu and Asthivaha Srotas. Their relationship is clinically important because Vata is located in Asthi, while excessive Vata and inadequate tissue nutrition are repeatedly associated with depletion, pain and structural deterioration. Objective: To critically analyse the Vata-Asthi relationship, the functional significance of Asthivaha Srotas and their combined role in the pathogenesis of Asthipradoshaja Vikara. Methods: A critical narrative review was undertaken using the Brihattrayi, principal commentarial interpretations and selected contemporary literature on bone remodelling and musculoskeletal ageing. Classical concepts were compared thematically under Dosha, Dhatu, Agni, Srotas and Samprapti. Results: The reviewed framework suggests that Asthi pathology cannot be reduced to a local defect of bone. Vata-provoking exposures, Agni and Asthi-dhatvagni disturbance, defective Dhatu-poshana and Asthivaha-srotodushti interact to produce either depletion-dominant or abnormal-growth manifestations. Asthi Kshaya may further favour Vata aggravation, generating a self-perpetuating cycle. Classical descriptions of teeth, nails, hair, pain, fragility and abnormal bony growth broaden the clinical field beyond a single modern diagnosis. Discussion: Contemporary bone-remodelling concepts provide useful analogies, but direct equivalence between Vata and neural regulation, or between Asthi Kshaya and osteoporosis, is methodologically unsound. Conclusion: Vata, Asthi and Asthivaha Srotas form a coherent systems-level model linking causation, tissue nutrition, transport and manifestation. This model supports early assessment, subtype-sensitive management and research based on operational Ayurvedic phenotypes.
Downloads
References
Agnivesha. Charaka Samhita. Revised by Charaka and Dridhabala. Relevant sections: Sutra Sthana (Dhatu-pradoshaja disorders and Dosha-Dhatu relations) and Vimana Sthana (Srotovimana). Consult the edition prescribed by the institution for exact verse numbering.
Sushruta. Sushruta Samhita. Relevant sections: Sutra Sthana (Dosha-Dhatu-Mala, Dhatu increase/decrease and Srotas) and Sharira Sthana (anatomical and Srotoviddha considerations). Consult the prescribed edition.
Vagbhata. Ashtanga Hridaya. Relevant sections: Sutra Sthana chapters on Dosha, Doshabheda, Doshadi-vijnana and tissue increase/decrease. Consult the prescribed edition.
Chakrapanidatta. Ayurveda Dipika commentary on Charaka Samhita. Use with the corresponding critically checked base text.
Dalhana. Nibandha Sangraha commentary on Sushruta Samhita. Use with the corresponding critically checked base text.
Arundatta. Sarvanga Sundara commentary on Ashtanga Hridaya. Use with the corresponding critically checked base text.
Hall JE, Hall ME. Guyton and Hall Textbook of Medical Physiology. 15th ed. Philadelphia: Elsevier; 2021.
Florencio-Silva R, Sasso GRS, Sasso-Cerri E, et al. Biology of bone tissue: structure, function, and factors that influence bone cells. BioMed Research International. 2015; 2015:421746.
Feng X, McDonald JM. Disorders of bone remodeling. Annual Review of Pathology. 2011; 6:121-145.
Compston JE, McClung MR, Leslie WD. Osteoporosis. Lancet. 2019;393(10169):364-376.
Raisz LG. Pathogenesis of osteoporosis: concepts, conflicts, and prospects. Journal of Clinical Investigation. 2005;115(12):3318-3325.
Raggatt LJ, Partridge NC. Cellular and molecular mechanisms of bone remodeling. Journal of Biological Chemistry. 2010;285(33):25103-25108.

