A CONCEPTUAL REVIEW ON RASANJANADI LEPA IN THE MANAGEMENT OF NADI VRANA (PILONIDAL SINUS) WITH SPECIAL REFERENCE TO GUNA, KARMA AND SAMPRAPTI VIGHATANA

Authors

  • Dr. Sarvagya Pathak
  • Dr Krishnanand C
  • Dr Gayathri S

DOI:

https://doi.org/10.5281/zenodo.21477525

Keywords:

Nadi Vrana, Pilonidal Sinus, Rasanjanadi Lepa, Shalya Tantra, Vrana Chikitsa, Shodhana, Ropana, Wound Healing.

Abstract

Background: Nadi Vrana is a chronic sinus tract disorder described in Sushruta Samhita, arising from inadequate management of Vrana (abscess). It is characterized by persistent purulent discharge, chronic inflammation, and delayed healing. Its clinical presentation and pathogenesis closely parallel Pilonidal Sinus, a condition involving sinus formation due to hair penetration and foreign body reaction.1,7,8 Despite advances in surgical techniques, recurrence rates remain high, necessitating effective conservative approaches.21

Aim: To evaluate the conceptual and pharmacological efficacy of Rasanjanadi Lepa in the management of Nadi Vrana with reference to Guna, Karma, and Samprapti Vighatana.

Materials and Methods: This is a conceptual review based on classical Ayurvedic texts — Sushruta Samhita, Charaka Samhita, and Ashtanga Hridaya — along with freely available modern scientific literature on pilonidal sinus and wound healing.1-6,7-11,18-21

Results: Rasanjanadi Lepa exhibits significant Shodhana (cleansing), Lekhana (debridement), Krimighna (antimicrobial), and Ropana (healing) properties, attributed to its Tikta-Kashaya

 

Rasa, Laghu-Ruksha Guna, Ushna Virya, and Katu Vipaka, which effectively counteract Kapha-Vata Dushti and promote tissue regeneration.3,5,6,15-17

Conclusion: Rasanjanadi Lepa provides a rational, mechanism-based, and non-invasive therapeutic approach for Nadi Vrana. Its multi-targeted action aligns with modern wound care principles, making it a promising conservative modality in the management of Pilonidal Sinus.18,21

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References

Classical Ayurvedic Texts

Acharya JT, editor. Sushruta Samhita of Sushruta. Nidana Sthana, Chapter 13. Reprint ed. Varanasi: Chaukhambha Surbharati Prakashan; 2019.

Acharya JT, editor. Sushruta Samhita of Sushruta. Chikitsa Sthana, Chapter 17. Reprint ed. Varanasi: Chaukhambha Surbharati Prakashan; 2019.

Acharya YT, editor. Charaka Samhita of Agnivesha. Chikitsa Sthana, Chapter 25. Varanasi: Chaukhambha Orientalia; 2018.

Acharya YT, editor. Charaka Samhita of Agnivesha. Sutra Sthana, Chapter 28. Varanasi: Chaukhambha Orientalia; 2018.

Murthy KRS, editor. Ashtanga Hridaya of Vagbhata. Sutra Sthana, Chapter 15. Varanasi: Chaukhambha Krishnadas Academy; 2017.

Bhavamishra. Bhavaprakasha Nighantu. Varanasi: Chaukhambha Bharati Academy; 2016.

Modern Open-Access References

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Jazi K, Rezaei M, Ahmadi N, et al. Surgical outcomes in pilonidal sinus disease. BMC Surg. 2025;25:486. doi:10.1186/s12893-025-03222-y.

Salehi V, Bakhshi A, Mohammadi S, et al. Perioperative management of pilonidal sinus disease. Perioper Med (Lond). 2022;11:1-9. doi:10.1186/s13741-021-00237-w.

Ambady AV, Nair RS, Kumar A, et al. Ayurvedic management approaches in chronic wounds. J Ayurveda Holist Med. 2025;13(1):1-8. doi:10.70066/jahm.v13i1.1548.

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Sidhu GS, Mani H, Gaddipati JP, et al. Curcumin enhances wound healing in streptozotocin-induced diabetic rats. Wound Repair Regen. 1998;6(2):167-177. doi:10.1046/j.1524-475X.1998.60211.x. PMID: 9776979.

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Herrod PJ, Boyd-Carson H, Doleman B, et al. Interventions for treating pilonidal sinus disease. Cochrane Database Syst Rev. 2022;5:CD013439.

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Published

2026-07-21

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Section

Review Article