MANDAGNI AND ITS EFFECT ON METABOLIC DISORDERS SUCH AS OBESITY AND DIABETES MELLITUS – AN AYURVEDIC AND MODERN PERSPECTIVE

Abstract

Background: In Ayurvedic philosophy, Agni (digestive fire) is fundamental to sustaining physiological equilibrium. A diminished Agni, referred to as Mandagni, is believed to be the underlying factor in the development of numerous diseases, notably metabolic disorders. Objective: This article investigates how the Ayurvedic notion of Mandagni contributes to the emergence of conditions such as obesity (Sthaulya) and diabetes mellitus (Madhumeha), aligning these concepts with modern medical insights. Methods: The study undertook an extensive review of classical Ayurvedic scriptures and current biomedical literature to examine the association between Mandagni and metabolic disturbances. Results: Dysfunctional Agni facilitates Ama (toxin) accumulation, disrupts tissue metabolism (Dhatu), and alters Dosha balance, leading to metabolic ailments. These Ayurvedic principles align with modern findings on impaired digestion, insulin resistance, gut dysbiosis, and inflammation. Conclusion: Revitalizing Agni through appropriate diet, lifestyle changes, and therapeutic interventions can be a viable method for managing and preventing obesity and diabetes.