THE EFFECT OF JATAMANSI PLANT IN HYPERTENSION -A DRUG REVIEW

Abstract

Background: Hypertension is a prevalent cardiovascular condition that significantly increases the risk of heart disease and stroke. Despite the availability of various antihypertensive medications, there is growing interest in natural remedies for managing blood pressure due to their holistic benefits and lower side effects. Jatamansi (Nardostachys jatamansi), a herb used in Ayurvedic medicine, has shown potential in controlling hypertension. Objective: To evaluate the effectiveness of Jatamansi in the management of hypertension through a comprehensive review of its pharmacological properties, mechanisms of action, and clinical efficacy. Methods: A detailed literature review was conducted, including Ayurvedic texts, modern pharmacological studies, and clinical trials. The study focused on the bioactive compounds in Jatamansi, its pharmacological actions related to blood pressure regulation, and evidence from clinical studies. Results: Jatamansi contains significant bioactive compounds such as jatamansone, nardostachone, and valeranal, which contribute to its therapeutic effects. The herb exhibits vasodilatory, antioxidant, and anti-inflammatory properties, which are crucial in managing hypertension. Clinical studies have demonstrated a significant reduction in both systolic and diastolic blood pressure in patients treated with Jatamansi extract compared to control groups. Discussion & Conclusion: Jatamansi shows promising potential as a natural antihypertensive agent. Its multifaceted approach to reducing blood pressure, through mechanisms such as vasodilation and stress reduction, makes it a valuable addition to hypertension management. Further clinical trials are necessary to establish standardized dosages and confirm long-term safety and efficacy.

Keywords: Jatamansi, Nardostachys jatamansi, hypertension, Ayurvedic medicine, blood pressure, vasodilation, antioxidant, anti-inflammatory.