A REVIEW OF RATE OF BIOENHANCER IN THE TREATMENT OF A CANCER

Deepial Priya Bennett, Bhanupriya Taram, Gyanesh Kumar Sahu

Abstract


Cancer is defined as the formation of abnormal cell which divides themselves into many in tissues and organs in other word- “cancer is result of the gathering of multiple genetic abnormality and epigenetic modification known as cancer metastasis. Bio enhancer’s are defined or known as those substances which increases the bioavailability of the drug .And due to increase in bioavailability the dose of the drug absorbs in the systemic circulation, which reduces the side effects. Novel drug delivery systems are known as the advancement of new techniques for drug delivery. The drug delivery  techniques  acquires the controlled release of drug, sustained release of drug, targeted delivery of drug to tissues and increases the duration of action.

Keywords: - Cancer, Novel drug delivery systems, Bioavailability.


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KHAN, J., ALEXANDER, A., AJAZUDDIN, SARAF, S., & SARAF, S. (2013). RECENT ADVANCES AND FUTURE PROSPECTS OF PHYTO-PHOSPHOLIPID COMPLEXATION TECHNIQUE FOR IMPROVING PHARMACOKINETIC PROFILE OF PLANT ACTIVES. JOURNAL OF CONTROLLED RELEASE, 168(1), 50–60.

AJAZUDDIN, & SARAF, S. (2010). APPLICATIONS OF NOVEL DRUG DELIVERY SYSTEM FOR HERBAL FORMULATIONS. FITOTERAPIA, 81(7), 680–689.

HOTALING, J. M., LAUFER, N., & ROSENWAKS, Z. (2018). INTRODUCTION. FERTILITY AND STERILITY, 109(1), 4–5.

ZUBAIR, H., & AHMAD, A. (2017). CANCER METASTASIS. INTRODUCTION TO CANCER METASTASIS, 3–12.

VEISEH, O., KIEVIT, F. M., ELLENBOGEN, R. G., & ZHANG, M. (2011). CANCER CELL INVASION: TREATMENT AND MONITORING OPPORTUNITIES IN NANOMEDICINE. ADVANCED DRUG DELIVERY REVIEWS, 63(8), 582–596.

AJAZUDDIN, ALEXANDER, A., QURESHI, A., KUMARI, L., VAISHNAV, P., SHARMA, M., … SARAF, S. (2014). ROLE OF HERBAL BIOACTIVES AS A POTENTIAL BIOAVAILABILITY ENHANCER FOR ACTIVE PHARMACEUTICAL INGREDIENTS. FITOTERAPIA, 97, 1–14.

KESARWANI, K., & GUPTA, R. (2013). BIOAVAILABILITY ENHANCERS OF HERBAL ORIGIN: AN OVERVIEW. ASIAN PACIFIC JOURNAL OF TROPICAL BIOMEDICINE, 3(4), 253–266.

AGRAWAL, U., SHARMA, R., MODY, N., DUBEY, S., & VYAS, S. P. (2016). IMPROVED ORAL BIOAVAILABILITY OF BIOACTIVES THROUGH LIPID-BASED NANOARCHITECTURES**DECLARATION OF INTEREST: THE AUTHORS REPORT NO CONFLICT OF INTEREST. SURFACE CHEMISTRY OF NANOBIOMATERIALS, 433–462.

RATHEE, P., KAMBOJ, A., & SIDHU, S. (2016). OPTIMIZATION AND DEVELOPMENT OF NISOLDIPINE NANO-BIOENHANCERS BY NOVEL ORTHOGONAL ARRAY (L27 ARRAY). INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 86, 556–561.

MEHTA, P., PAWAR, A., MAHADIK, K., & BOTHIRAJA, C. (2018). EMERGING NOVEL DRUG DELIVERY STRATEGIES FOR BIOACTIVE FLAVONOL FISETIN IN BIOMEDICINE. BIOMEDICINE & PHARMACOTHERAPY, 106, 1282–1291.

DELGADO-ROSALES, E. E., QUINTANAR-GUERRERO, D., PIÑÓN-SEGUNDO, E., MAGAÑA-VERGARA, N. E., LEYVA-GÓMEZ, G., MARTÍNEZ-MARTÍNEZ, F. J., & MENDOZA-MUÑOZ, N. (2018). NOVEL DRUG DELIVERY SYSTEMS BASED ON THE ENCAPSULATION OF SUPERPARAMAGNETIC NANOPARTICLES INTO LIPID NANOCOMPOSITES. JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY, 46, 259–267.

DHANASEKARAN, H. R., SHARMA, C. P., & HARIDOSS, P. (2018). DRUG DELIVERY NANOSYSTEMS—AN INTRODUCTION. DRUG DELIVERY NANOSYSTEMS FOR BIOMEDICAL APPLICATIONS, 1–12.

PATWARDHAN, B., MUTALIK, G., & TILLU, G. (2015). DRUG DISCOVERY AND AYURVEDA. INTEGRATIVE APPROACHES FOR HEALTH, 229–258.

ALEXANDER, A., DWIVEDI, S., AJAZUDDIN, GIRI, T. K., SARAF, S., SARAF, S., & TRIPATHI, D. K. (2012). APPROACHES FOR BREAKING THE BARRIERS OF DRUG PERMEATION THROUGH TRANSDERMAL DRUG DELIVERY. JOURNAL OF CONTROLLED RELEASE, 164(1), 26–40.

AJAZUDDIN, & SARAF, S. (2010). APPLICATIONS OF NOVEL DRUG DELIVERY SYSTEM FOR HERBAL FORMULATIONS. FITOTERAPIA, 81(7), 680–689.

PINGALE, P. L., PANDHARINATH, R. R., & SHROTRIYA, P. G. (2014). STUDY OF HERBAL BIOENHANCERS ON VARIOUS CHARACTERISTICS OF ISONIAZID AND RIFAMPICIN MICROSPHERES. INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES, 21, 235.

BI, X., YUAN, Z., QU, B., ZHOU, H., LIU, Z., & XIE, Y. (2018). PIPERINE ENHANCES THE BIOAVAILABILITY OF SILYBIN VIA INHIBITION OF EFFLUX TRANSPORTERS BCRP AND MRP2. PHYTOMEDICINE

BASTAKI, M., AUBANEL, M., BAUTER, M., CACHET, T., DEMYTTENAERE, J., DIOP, M. M., … TAYLOR, S. V. (2018). ABSENCE OF ADVERSE EFFECTS FOLLOWING ADMINISTRATION OF PIPERINE IN THE DIET OF SPRAGUE-DAWLEY RATS FOR 90 DAYS. FOOD AND CHEMICAL TOXICOLOGY, 120, 213–221.

KHAMIS, A. A. A., ALI, E. M. M., EL-MONEIM, M. A. A., ABD-ALHASEEB, M. M., EL-MAGD, M. A., & SALIM, E. I. (2018). HESPERIDIN, PIPERINE AND BEE VENOM SYNERGISTICALLY POTENTIATE THE ANTICANCER EFFECT OF TAMOXIFEN AGAINST BREAST CANCER CELLS. BIOMEDICINE & PHARMACOTHERAPY, 105, 1335–1343.

BI, X., YUAN, Z., QU, B., ZHOU, H., LIU, Z., & XIE, Y. (2018). PIPERINE ENHANCES THE BIOAVAILABILITY OF SILYBIN VIA INHIBITION OF EFFLUX TRANSPORTERS BCRP AND MRP2. PHYTOMEDICINE.

KUMAR, S., BHANDARI, C., SHARMA, P., & AGNIHOTRI, N. (2018). ROLE OF PIPERINE IN CHEMORESISTANCE. ROLE OF NUTRACEUTICALS IN CHEMORESISTANCE TO CANCER, 259–286.

GUNASEKARAN, V., ELANGOVAN, K., & NIRANJALI DEVARAJ, S. (2017). TARGETING HEPATOCELLULAR CARCINOMA WITH PIPERINE BY RADICAL-MEDIATED MITOCHONDRIAL PATHWAY OF APOPTOSIS: AN IN VITRO AND IN VIVO STUDY. FOOD AND CHEMICAL TOXICOLOGY, 105, 106–118.

GREENSHIELDS, A. L., DOUCETTE, C. D., SUTTON, K. M., MADERA, L., ANNAN, H., YAFFE, P. B., … HOSKIN, D. W. (2015). PIPERINE INHIBITS THE GROWTH AND MOTILITY OF TRIPLE-NEGATIVE BREAST CANCER CELLS. CANCER LETTERS, 357(1), 129–140.

CIRILLO, G., VITTORIO, O., HAMPEL, S., IEMMA, F., PARCHI, P., CECCHINI, M., … PICCI, N. (2013). QUERCETIN NANOCOMPOSITE AS NOVEL ANTICANCER THERAPEUTIC: IMPROVED EFFICIENCY AND REDUCED TOXICITY. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 49(3), 359–365.

BAKSI, R., SINGH, D. P., BORSE, S. P., RANA, R., SHARMA, V., & NIVSARKAR, M. (2018). IN VITRO AND IN VIVO ANTICANCER EFFICACY POTENTIAL OF QUERCETIN LOADED POLYMERIC NANOPARTICLES. BIOMEDICINE & PHARMACOTHERAPY, 106, 1513–1526.

YANG, X., ZHANG, W., ZHAO, Z., LI, N., MOU, Z., SUN, D., … LIN, Y. (2017). QUERCETIN LOADING CDSE/ZNS NANOPARTICLES AS EFFICIENT ANTIBACTERIAL AND ANTICANCER MATERIALS. JOURNAL OF INORGANIC BIOCHEMISTRY, 167, 36–48.

CIRILLO, G., VITTORIO, O., HAMPEL, S., IEMMA, F., PARCHI, P., CECCHINI, M., … PICCI, N. (2013). QUERCETIN NANOCOMPOSITE AS NOVEL ANTICANCER THERAPEUTIC: IMPROVED EFFICIENCY AND REDUCED TOXICITY. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 49(3), 359–365.

TANG, S.-M., DENG, X., LI, Q., GE, X., & MIAO, L. (2018). SA1467 - ANTICANCER EFFECTS OF QUERCETIN ON CHOLANGIOCARCINOMA. GASTROENTEROLOGY, 154(6), S–1122–S–1123.

BARTNIK, M., & FACEY, P. C. (2017). GLYCOSIDES. PHARMACOGNOSY, 101–161.

TILOKE, C., ANAND, K., GENGAN, R. M., & CHUTURGOON, A. A. (2018). MORINGA OLEIFERA AND THEIR PHYTONANOPARTICLES: POTENTIAL ANTIPROLIFERATIVE AGENTS AGAINST CANCER. BIOMEDICINE & PHARMACOTHERAPY, 108, 457–466.

ARUNA, K., & SIVARAMAKRISHNAN, V. M. (1992). ANTICARCINOGENIC EFFECTS OF SOME INDIAN PLANT PRODUCTS. FOOD AND CHEMICAL TOXICOLOGY, 30(11), 953–956.

WU, J.-C., ZHANG, Y.-P., ZHENG, Y.-X., & PENG, X.-M. (2018). POLLEN MEDIATED GENE FLOW IN A SMALL EXPERIMENTAL POPULATION OF MORINGA OLEIFERA LAM. (MORINGACEAE). INDUSTRIAL CROPS AND PRODUCTS, 117, 28–33.

TILOKE, C., ANAND, K., GENGAN, R. M., & CHUTURGOON, A. A. (2018). MORINGA OLEIFERA AND THEIR PHYTONANOPARTICLES: POTENTIAL ANTIPROLIFERATIVE AGENTS AGAINST CANCER. BIOMEDICINE & PHARMACOTHERAPY, 108, 457–466.

SAUCEDO-POMPA, S., TORRES-CASTILLO, J. A., CASTRO-LÓPEZ, C., ROJAS, R., SÁNCHEZ-ALEJO, E. J., NGANGYO-HEYA, M., & MARTÍNEZ-ÁVILA, G. C. G. (2018). MORINGA PLANTS: BIOACTIVE COMPOUNDS AND PROMISING APPLICATIONS IN FOOD PRODUCTS. FOOD RESEARCH INTERNATIONAL, 111, 438–450.

KUETE, V. (2017). MORINGA OLEIFERA. MEDICINAL SPICES AND VEGETABLES FROM AFRICA, 485–496.

LIU, H.-T., & HO, Y.-S. (2018). ANTICANCER EFFECT OF CURCUMIN ON BREAST CANCER AND STEM CELLS. FOOD SCIENCE AND HUMAN WELLNESS, 7(2), 134–137.

WANG, J. Q., WANG, X., WANG, Y., TANG, W. J., SHI, J. B., & LIU, X. H. (2018). NOVEL CURCUMIN ANALOGUE HYBRIDS: SYNTHESIS AND ANTICANCER ACTIVITY. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 156, 493–509.

ASABUWA NGWABEBHOH, F., ILKAR ERDAGI, S., & YILDIZ, U. (2018). PICKERING EMULSIONS STABILIZED NANOCELLULOSIC-BASED NANOPARTICLES FOR COUMARIN AND CURCUMIN NANOENCAPSULATIONS: IN VITRO RELEASE, ANTICANCER AND ANTIMICROBIAL ACTIVITIES. CARBOHYDRATE POLYMERS, 201, 317–328.

DARWISH, S., MOZAFFARI, S., PARANG, K., & TIWARI, R. (2017). CYCLIC PEPTIDE CONJUGATE OF CURCUMIN AND DOXORUBICIN AS AN ANTICANCER AGENT. TETRAHEDRON LETTERS, 58(49), 4617–4622.

KHAN, S., IMRAN, M., BUTT, T. T., ALI SHAH, S. W., SOHAIL, M., MALIK, A., … HUSSAIN, Z. (2018). CURCUMIN BASED NANOMEDICINES AS EFFICIENT NANOPLATFORM FOR TREATMENT OF CANCER: NEW DEVELOPMENTS IN REVERSING CANCER DRUG RESISTANCE, RAPID INTERNALIZATION, AND IMPROVED ANTICANCER EFFICACY. TRENDS IN FOOD SCIENCE & TECHNOLOGY, 80, 8–22.

PRÖHL, M., SCHUBERT, U. S., WEIGAND, W., & GOTTSCHALDT, M. (2016). METAL COMPLEXES OF CURCUMIN AND CURCUMIN DERIVATIVES FOR MOLECULAR IMAGING AND ANTICANCER THERAPY. COORDINATION CHEMISTRY REVIEWS, 307, 32–41.

TANG, H., MURPHY, C. J., ZHANG, B., SHEN, Y., VAN KIRK, E. A., MURDOCH, W. J., & RADOSZ, M. (2010). CURCUMIN POLYMERS AS ANTICANCER CONJUGATES. BIOMATERIALS, 31(27), 7139–7149.

BI, Y., MIN, M., SHEN, W., & LIU, Y. (2018). GENISTEIN INDUCED ANTICANCER EFFECTS ON PANCREATIC CANCER CELL LINES INVOLVES MITOCHONDRIAL APOPTOSIS, G 0 /G 1 CELL CYCLE ARREST AND REGULATION OF STAT3 SIGNALLING PATHWAY. PHYTOMEDICINE, 39, 10–16.

MUKUND, V., MUKUND, D., SHARMA, V., MANNARAPU, M., & ALAM, A. (2017). GENISTEIN: ITS ROLE IN METABOLIC DISEASES AND CANCER. CRITICAL REVIEWS IN ONCOLOGY/HEMATOLOGY, 119, 13–22.

EE, J.-Y., KIM, H. S., & SONG, Y.-S. (2012). GENISTEIN AS A POTENTIAL ANTICANCER AGENT AGAINST OVARIAN CANCER. JOURNAL OF TRADITIONAL AND COMPLEMENTARY MEDICINE, 2(2), 96–104.

CHEN, Q.-H., YU, K., ZHANG, X., CHEN, G., HOOVER, A., LEON, F., … HARINANTENAINA RAKOTONDRAIBE, L. (2015). A NEW CLASS OF HYBRID ANTICANCER AGENTS INSPIRED BY THE SYNERGISTIC EFFECTS OF CURCUMIN AND GENISTEIN: DESIGN, SYNTHESIS, AND ANTI-PROLIFERATIVE EVALUATION. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 25(20), 4553–4556.

GANAI, A. A., & FAROOQI, H. (2015). BIOACTIVITY OF GENISTEIN: A REVIEW OF IN VITRO AND IN VIVO STUDIES. BIOMEDICINE & PHARMACOTHERAPY, 76, 30–38.

BACANLI, M., BAŞARAN, A. A., & BAŞARAN, N. (2018). THE MAJOR FLAVONOID OF GRAPEFRUIT: NARINGIN. POLYPHENOLS: PREVENTION AND TREATMENT OF HUMAN DISEASE, 37–44.

ERDOGAN, S., DOGANLAR, O., DOGANLAR, Z. B., & TURKEKUL, K. (2017). NARINGIN SENSITIZES HUMAN PROSTATE CANCER CELLS TO PACLITAXEL THERAPY. PROSTATE INTERNATIONAL.

FENG, T., WANG, K., LIU, F., YE, R., ZHU, X., ZHUANG, H., & XU, Z. (2017). STRUCTURAL CHARACTERIZATION AND BIOAVAILABILITY OF TERNARY NANOPARTICLES CONSISTING OF AMYLOSE, Α-LINOLEIC ACID AND Β-LACTOGLOBULIN COMPLEXED WITH NARINGIN. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 99, 365–374.

ERDOGAN, S., DOGANLAR, O., DOGANLAR, Z. B., & TURKEKUL, K. (2017). NARINGIN SENSITIZES HUMAN PROSTATE CANCER CELLS TO PACLITAXEL THERAPY. PROSTATE INTERNATIONAL.

THANGAVEL, P., & VAIYAPURI, M. (2013). ANTIPROLIFERATIVE AND APOPTOTIC EFFECTS OF NARINGIN ON DIETHYLNITROSAMINE INDUCED HEPATOCELLULAR CARCINOMA IN RATS. BIOMEDICINE & AGING PATHOLOGY, 3(2), 59–64.

SONG, L., LIU, D., ZHAO, Y., HE, J., KANG, H., DAI, Z., … XUE, X. (2018). SINOMENINE REDUCES GROWTH AND METASTASIS OF BREAST CANCER CELLS AND IMPROVES THE SURVIVAL OF TUMOR-BEARING MICE THROUGH SUPPRESSING THE SHH PATHWAY. BIOMEDICINE & PHARMACOTHERAPY, 98, 687–693.

DENG, F., MA, Y.-X., LIANG, L., ZHANG, P., & FENG, J. (2018). THE PRO-APOPTOSIS EFFECT OF SINOMENINE IN RENAL CARCINOMA VIA INDUCING AUTOPHAGY THROUGH INACTIVATING PI3K/AKT/MTOR PATHWAY. BIOMEDICINE & PHARMACOTHERAPY, 97, 1269–1274.

CHAN, K., LIU, Z. Q., JIANG, Z. H., ZHOU, H., WONG, Y. F., XU, H.-X., & LIU, L. (2006). THE EFFECTS OF SINOMENINE ON INTESTINAL ABSORPTION OF PAEONIFLORIN BY THE EVERTED RAT GUT SAC MODEL. JOURNAL OF ETHNOPHARMACOLOGY, 103(3), 425–432.

YING, J., ZHANG, M., QIU, X., & LU, Y. (2018). THE POTENTIAL OF HERB MEDICINES IN THE TREATMENT OF ESOPHAGEAL CANCER. BIOMEDICINE & PHARMACOTHERAPY, 103, 381–390.

CAI, Y., ZHAO, B., LIANG, Q., ZHANG, Y., CAI, J., & LI, G. (2017). THE SELECTIVE EFFECT OF GLYCYRRHIZIN AND GLYCYRRHETINIC ACID ON TOPOISOMERASE IIΑ AND APOPTOSIS IN COMBINATION WITH ETOPOSIDE ON TRIPLE NEGATIVE BREAST CANCER MDA-MB-231 CELLS. EUROPEAN JOURNAL OF PHARMACOLOGY, 809, 87–97.

DONG, S., INOUE, A., ZHU, Y., TANJI, M., & KIYAMA, R. (2007). ACTIVATION OF RAPID SIGNALING PATHWAYS AND THE SUBSEQUENT TRANSCRIPTIONAL REGULATION FOR THE PROLIFERATION OF BREAST CANCER MCF-7 CELLS BY THE TREATMENT WITH AN EXTRACT OF GLYCYRRHIZA GLABRA ROOT. FOOD AND CHEMICAL TOXICOLOGY, 45(12), 2470–2478.

IMAI, T., SAKAI, M., OHTAKE, H., AZUMA, H., & OTAGIRI, M. (2005). ABSORPTION-ENHANCING EFFECT OF GLYCYRRHIZIN INDUCED IN THE PRESENCE OF CAPRIC ACID. INTERNATIONAL JOURNAL OF PHARMACEUTICS, 294(1-2), 11–21.

SHI, L., TANG, C., & YIN, C. (2012). GLYCYRRHIZIN-MODIFIED O-CARBOXYMETHYL CHITOSAN NANOPARTICLES AS DRUG VEHICLES TARGETING HEPATOCELLULAR CARCINOMA. BIOMATERIALS, 33(30), 7594–7604.

EL-NABARAWY, M. A., EL-KAFAFI, S. H., HAMZA, M. A., & OMAR, M. A. (2015). THE EFFECT OF SOME FACTORS ON STIMULATING THE GROWTH AND PRODUCTION OF ACTIVE SUBSTANCES IN ZINGIBER OFFICINALE CALLUS CULTURES. ANNALS OF AGRICULTURAL SCIENCES, 60(1), 1–9.

DA SILVEIRA VASCONCELOS, M., MOTA, E. F., GOMES-ROCHETTE, N. F., NUNES-PINHEIRO, D. C. S., NABAVI, S. M., & DE MELO, D. F. (2019). GINGER (ZINGIBER OFFICINALE ROSCOE). NONVITAMIN AND NONMINERAL NUTRITIONAL SUPPLEMENTS, 235–239.

SAXENA, R., & ANEJA, R. (2018). MULTITALENTED GINGER AND ITS CLINICAL DEVELOPMENT FOR CANCER TREATMENT. ROLE OF NUTRACEUTICALS IN CHEMORESISTANCE TO CANCER, 351–370.

CHENG, X.-L., LIU, Q., PENG, Y.-B., QI, L.-W., & LI, P. (2011). STEAMED GINGER (ZINGIBER OFFICINALE): CHANGED CHEMICAL PROFILE AND INCREASED ANTICANCER POTENTIAL. FOOD CHEMISTRY, 129(4), 1785–1792.

MANDAL, M., & MANDAL, S. (2016). CUMIN (CUMINUM CYMINUM L.) OILS. ESSENTIAL OILS IN FOOD PRESERVATION, FLAVOR AND SAFETY, 377–383.

ARUNA, K., & SIVARAMAKRISHNAN, V. M. (1992). ANTICARCINOGENIC EFFECTS OF SOME INDIAN PLANT PRODUCTS. FOOD AND CHEMICAL TOXICOLOGY, 30(11), 953–956.

SOWBHAGYA, H. B., SRINIVAS, P., PURNIMA, K. T., & KRISHNAMURTHY, N. (2011). ENZYME-ASSISTED EXTRACTION OF VOLATILES FROM CUMIN (CUMINUM CYMINUM L.) SEEDS. FOOD CHEMISTRY, 127(4), 1856–1861.


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