• V.O. Malanchuk Bogomolets National Medical University
  • V. S. Shvydchenko Bogomolets National Medical University
  • N. A. Galatenko Institute of Macromolecular Chemistry of National Academy of Sciences of Ukraine
  • D. V. Kulesh Institute of Macromolecular Chemistry of National Academy of Sciences of Ukraine


The issue of the influence of various materials for bone regeneration and its optimization remains relevant. Morpho-histological studies of the biocompatibility and bioactivity were performed on 36 white laboratory rats and have shown that folic acid in the composite material inhibited the exudative phase of inflammation. Physicochemical and biological properties of the folate-polymer composites provide an opportunity for eliminating of the periradicular bone defects and prevention of the teeth displacement.

Key words: periradicular bone defects, folate-polymer composites, implantation, biodegradation, bone formation.


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How to cite this article:

V.O. Malanchuk, V.S. Shvydchenko, N.A. Galatenko and D.V. Kulesh; Experimental study of the possibility of using folate-polymer composites for the surgical treatment of Periradicular bone defects; International Journal of Nursing and Medical Science 2018; 7 (4), 30-38.