SAPINDUS MUKOROSSI: A COMPLETE REVIEW ON PHARMACOLOGY, PHYTOCHEMISTRY AND TOXICOLOGICAL DATA
Abstract
A deciduous tree known as Sapindus mukorossi is found in Asia's tropical and subtropical climates. It has been used for many years to treat a variety of illnesses in Ayurvedic and traditional Chinese medicine. This article examines S. mukorossi pharmacological, phytochemical, and ethnomedicinal applications. The current review's objective is to give a concise overview of the phytochemical makeup, pharmacological characteristics, and toxicological research of this adaptable tree. Oleanane, dammarane, tricullane, and lupane type triterpenoid saponins are the primary plant ingredients that have been isolated and identified from various portions of this plant. All varieties of triterpenoid saponins have been described with their chemical names and structures. Numerous studies have been done to show that the plant has the potential to be used as a spermicide, contraceptive, hepatoprotective, emetic, anti-inflammatory, and antiprotozoal. Toxicological testing of Sapindus mukorossi on Wistar rats has also been done, which is shown to have LD50 above 5000 mg/kg in rats.
KEYWORDS
Sapindus mukorossi; Pharmacological effects; Saponins Isolation; Phytochemistry; Traditional medicine; Acute Toxicity.
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