A NOBLE STUDY ON PHARMACEUTICAL AND PHYTOCHEMICAL ANALYSIS OF NIMBATWAGADI GHANAVATI -A POLYHERBAL FORMULATION

Authors

  • Rohini HD AYURVEDA MAHAVIDYALAYA HUBLI RGUHS

Abstract

Nimbatwagadi kashaya is a polyherbal preparation which is in liquid form and bitter for palatability many times the patients reject or discontinue taking Ayurveda medicine because of palatability. Different dosage forms are explained in the Ayurveda system of medicine hence the present study was taken up for the preparation of ghanavati of Nimbatwagadi kashayam of sahasraya yoga kashaya prakarana. The prepared vati was subjected for physciochemical and phytochemical analysis, HPTLC, microbial load as per the who guidelines .efforts were made to laydown the analytical standars for the Nimbatwagadi ghanavati which were not reported till date. Loss  on drying 3.767% ,  Ash value-14.064%, Acid insoluble ash 1.04%, Water soluble extractive-74.832,Alcohol soluble extractive-8.514%, Hardness-3.0kg/cm, Friability-0.400%, Disintegration-30 min,  Ph-5.58%,  in HPTLC of Nimbatwagadi Ghanavati maximum five sports at short UV and 4 spots at long UV. Microorganisms in the formulation was zero.

Key words- Nimbatwagadi Ghanavati, Physico chemical Analysis, Phytochemical Analysis, HPTLC

References

Devendra Josi, Introduction to Ayurvedic Pharmaceutics, Chaukhamba Orientalia, Varanasi , 2014, chapter1, p3.

Nishteswar, Sahasrayogam, kashaya prakarana, 2nd edition 2008, Chowkhamba Krishnadas Academy.varanasi, p37.

Dr shobha G Hiremath –A Text Book of Bahisajya –Kalpana ,IBH prakashana,Bangalore,2016,chapter 9,p103.

Dr shobha G Hiremath –A Text Book of Bahisajya –Kalpana ,IBH prakashana, Bangalore, 2016,chapter 10,p137.

P. Nainwal Dev -Pharmacovigilance of Herbal Medicines: An Intangible Approach IJPSR, 2010,Vol 1/11.

https://cdn.who.int/media/docs/default-source/medicines/norms-and-standards/guidelines/production/trs1010-annex2-who-gmp-manufacture-herbal-medicines.pdf?sfvrsn=9241812_0&download=true.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3361938/

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Published

2023-02-16

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Section

Original Research Article