Background: Bullous Pemphigoid [BP] is a rare autoimmune disease commonly affecting elderly age group, characterized by subepidermal bullous formation and pruritus. The standard conventional management with corticosteroids is reported to have severe adverse effects which add to the morbidity of the patient. In this scenario it is prudent to explore the role of alternative medicines in the management of rare autoimmune disorders like BP.

Methods: A case of BP treated with Individualized Homoeopathic medicine Natrum muriaticum in ultrahigh dilution is presented here. The case was followed-up with documentation of symptoms, BPDAI [Bullous Pemphigoid Disease Area Index] score and photographs with the patient consent. The case reporting is done according to the HOM-CASE guidelines, extension of CARE guidelines.

Results: The lesions resolved within 3 months of Homoeopathic treatment. No adverse events were reported during the course of treatment. BPDAI score reduced to 0 from baseline objective total score of 60/120 and baseline subjective score of 30/30.

Conclusion: The present case report shows that BP may respond to Homoeopathic treatment and there was ‘complete remission on therapy’ as per Definition of Bullous pemphigoid. Further research is warranted in this direction to establish the efficacy of ultrahigh dilutions in the management of Auto immune disorders.

Author Biographies

  • Vinitha Edavattath Ramanan, CCRH
    Research Officer [S-1]/Assistant Professor, Department of Practice of Medicine, NHRIMH Kottayam, Under CCRH, Ministry of Ayush
  • Dr. Reshma Radhakrishnan, CCRH
    JRF, NHRIMH Kottayam, Under CCRH, Ministry of Ayush


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Case Study Research Article