IMPACT OF VIRUDDHA AHARA ON HEPATIC PATHOPHYSIOLOGY: EXPLORING AYURVEDIC INSIGHTS AND MODERN CO-RELATION

Abstract

Background: The concept of Viruddha Ahara (incompatible diet) is well-documented in Ayurveda and is believed to have a significant impact on systemic health, including hepatic function. Ayurveda emphasizes that the persistent consumption of Viruddha Ahara leads to metabolic disturbances and aggravates Dosha, resulting in various pathophysiological conditions affecting the liver. This study explores the Ayurvedic perspective on Viruddha Ahara and its implications on hepatic pathophysiology while correlating these insights with modern medical understanding. Aim & Objective: To analyze the impact of Viruddha Ahara on hepatic pathophysiology through Ayurvedic principles and modern scientific correlations Methods: A comprehensive review of classical Ayurvedic texts and modern literature was conducted to understand the pathophysiological changes in the liver due to Viruddha Ahara. Ayurvedic principles related to Agni, Ama formation, and Dosha imbalance were critically analyzed. Additionally, modern scientific studies on dietary incompatibilities, hepatotoxicity, and liver disorders were reviewed to establish a correlation. Results: Ayurvedic texts suggest that Viruddha Ahara disrupts Agni (digestive fire), leading to Ama (toxins) accumulation, which impairs liver function. Specific dietary incompatibilities, such as milk with fish, honey with ghee in equal proportions, and fruit consumption with dairy, are believed to cause metabolic imbalances. Modern research supports these concepts by demonstrating the effects of dietary incompatibilities on gut microbiota, metabolic endotoxemia, oxidative stress, and inflammatory responses, contributing to liver dysfunctions such as non-alcoholic fatty liver disease (NAFLD) and hepatocellular injury. Conclusion: The findings indicate a strong association between Viruddha Ahara and hepatic pathophysiology from both Ayurvedic and modern perspectives. Understanding these dietary incompatibilities can aid in preventive and therapeutic approaches for liver disorders. Future research is required to validate Ayurvedic dietary principles through clinical and experimental studies for integrative hepatology.