RECOMBINANT ANTIBIOTICS IN CANCER THERAPY- A REVIEW

Aksa Alex, Ahsinul Muhusina, Pooja Raj R, Smruthy Santhosh, Shravya Suresh

Abstract


Cancer is the disease of uncontrolled cellular growth in which abnormal cells develop and reproduce. Decades of biomedical research in developed nations have resulted in many effective interventions that affect cancer incidence and mortality. The most common cancer treatments are restricted to surgery, conventional chemotherapy and radiotherapy. Although these conventional anticancer therapies are effective in the management of many patients, these therapies are ineffective for approximately half of cancer sufferers. Thus, new strategies are being developed and used to treat cancer by improving, supplementing or replacing conventional methods. Anticancer antibiotics have made a successful impact in the field of chemotherapy. For most of them, DNA is the molecular target. Some act as DNA intercalators or some prevent DNA rapair among other mechanism of actions. Some other agents showed that stimulation and enhancement of existing host defense mechanism in one of the additional ways that these chemotherapeutic agents exert their effects.

Keywords:

                Cancer, Recombinant therapy, tumour, leukemia, haematopoiec cells, sarcoma.


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References


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