IN VITRO ANTIOXIDANT ACTIVITY ON ETHANOLIC EXTRACT OF BLACK GRAPES (VITIS VINIFERA) AND PRELIMINARY PHYTOCHEMICAL SCREENING

Authors

  • Shital Dange Department of Pharmaceutical Analysis, Sree Dattha Institute of Pharmacy, Sheriguda, Hyderabad-501510, Telangana, India
  • K Janaki Department of Pharmaceutical Analysis, Sree Dattha Institute of Pharmacy, Sheriguda, Hyderabad-501510, Telangana, India
  • D. Deepika Department of Pharmaceutical Analysis, Sree Dattha Institute of Pharmacy, Sheriguda, Hyderabad-501510, Telangana, India
  • V. Kavya Sri Department of Pharmaceutical Analysis, Sree Dattha Institute of Pharmacy, Sheriguda, Hyderabad-501510, Telangana, India
  • D Karthik Department of Pharmaceutical Analysis, Sree Dattha Institute of Pharmacy, Sheriguda, Hyderabad-501510, Telangana, India

Abstract

The aim of study is to assess the preliminary phytochemical screening and in vitro antioxidant activity of ethanolic extract obtained from fruits of black grapes of Vitis vinifera. The assessment of antioxidant activity performed by in vitro method using DPPH (2,2’-diphenyl-1-picrylhydrazyl), reducing power and hydrogen peroxide. Black grapes have good source of reducing sugars, Flavanoids, Saponins and Monosaccharides. The ethanolic extract of black grapes has been reported to show high scavenging activity against the DPPH free radical generating system. The antiradical activity of test compound and ascorbic acid against DPPH ic50 values were found to be as 17.3±0.71, to 57.7±0.5 increased with respectively concentrations with that of reference standard, ascorbic acid (47.6±0.48 to 89.1±0.51). Antioxidant activity of black grapes was found to be good and about near to the standards.

Keywords Vitis Vinifera, Antioxidant activity

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How to cite this article:

Shital Dange1*, K. Janaki, D. Deepika, V. Kavya Sri, D. Karthik; In vitro antioxidant activity on ethanolic extract of Black Grapes (Vitis Vinifera) and preliminary phytochemical screening; Panacea Journal of Pharmacy and Pharmaceutical Sciences 2018:7(3); 35-46.

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Published

2018-09-29

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Original Research Article