PHYTOCHEMICAL SCREENING AND IN VITRO ANTIDIABETIC AND ANTI-INFLAMMATORY ACTIVITY OF HERBAL EXTRACT OF XANTHIUM STRUMARIUM

Authors

  • Chandraprakash Godaniya
  • Anshita Gupta
  • Dr. Vivek Gupta

Abstract

This study deals with the Phytochemical screening and in vitro antidiabetic and anti-inflammatory activity of herbal extract of Xanthium strumarium. The leaves of the plant were collected & subjected to extraction by pet ether & hydroalcoholic solvent. Further the hydroalcoholic extract was screened for qualitative & quantitative estimation of phytochemicals along with TLC. Further the anti- diabetic & anti -inflammatory effect was also evaluated. The results showed that the percentage yield of pet ether extract of Xanthium strumarium was found to be 2.53% while for hydroalcoholic extract it was found to be 8.67%. Phytochemical screening revealed the presence of carbohydrate, proteins, saponins, flavonoids & tannins & phenolics. The TLC profile has revealed that presence of flavonoids in the tested plant extract. The phenolic & flavonoid content in hydroalcoholic extract of Xanthium strumarium was found to be 0.352mg/100mg & 0.674mg/100mg of dried extract. The anti -diabetic activity of plant was estimated by alpha amylase assay. The IC 50 value for standard acarbose was found to be 35.33% while for Extract of Xanthium strumarium it was found to be 335.60 %. The anti -inflammatory activity was performed by using Diclofenac sodium as standard. The IC 50 for Diclofenac was found to be 230.13 % while for hydroalcoholic extract of Xanthium strumarium the IC 50 value was found to be 322.09 %. So it can be concluded that Xanthium strumarium have potent anti -inflammatory & Anti diabetic effect.

Key words: Xanthium strumarium, Antidiabetic, Anti-inflammatory, Evaluation

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Published

2022-12-23

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Original Research Article