A COMPREHENSIVE REVIEW ON PRISHNIPARNI -DESMODIUMGANGETICUM (LINN.) DC.

Authors

  • Aswathy Krishna R
  • Ansary P Y
  • Sara Monsy Oommen
  • Shincy Mol V V

Abstract

Prishniparni is a significant and well-known drug expoundly discussed in the Ayurvedic classics. The illustration and description of the drug commences from the Vedic period itself. Various therapeutic potential and uses of the drug is described in Charaka Samhita, Susrutha Samhita, Ashtanga Hridaya and Chikitsa Manjari. In the Ashtanga hridaya it is described as one among the amshumatidwaya and as an ingredient of the group of dashamoola. The drug Prishniparni is extensively described along with its synonyms, properties and uses in various Nighantus. The plant is botanically identified to be Desmodiumgangeticum (Linn.) DC. belonging to the family Fabaceae, which is an erect diffusely branched under shrub or herb. It has poorly developed main root and prominent lateral roots. In Kerala Desmodiumgangeticum (Linn.) DC. is Prishniparniand is commonly known as orila. The plant is a rich source of alkaloids, flavonoids, steroids and glycosides. The plant is known to exhibit anti-oxidant, cardioprotective, anti-hypertrophic, anti-ulcer, hepatoprotective, anti-amnesic, wound healing and, anti-inflammatory activities.

Key words: Prishniparni, Desmodiumgangeticum (Linn.) DC., Ayurvedic classics Pharmacological activity.

References

Vagbhata. Ashtanga Hridayam Vol I. Trans Prof. K R Srikantha Murthy.9thed.Varanasi: Chaukhambha Krishnadas Academy; 2012. Sutrasthana, Chapter6. Annasvarupavijnaneeya adhyaya, Sloka 167-168;p.107.

Susrutha. Illustrated Susruta Samhita Vol I. Trans Prof. KR Srikantha Murthy.Reprint ed. Varanasi: Chaukhambha orientalia; 2012. Sutrasthana, Chapter 38. Dravya sangrahaneeyaadyaya, Sloka 71;p.274.

Dr. V. W Karambelkar, The Atharva-veda and the Ayur-veda. Varanasi: Chaukhamba Krishnadas Academy; 2003.p.304.

Ram Gopal Shastry, Vedommein Ayurveda. Madanamohana Lala Ayurvedika; 2013.p.242.

Agnivesa. Charaka Samhita Vol IV. Trans R K Sharma, Bhagwan Dash. Reprint ed. Varanasi: Chaukambha Sanskrit series office; 2011. Chikitsasthana, Chapter 26. Trimarmeeyachikitsa, sloka 73-75; p.490.

Agnivesa. Charaka Samhita Vol IV. Trans R K Sharma, Bhagwan Dash. Reprint ed. Varanasi: Chaukambha Sanskrit series office; 2011. Chikitsasthana, Chapter 26. Trimarmeeyachikitsa, sloka 90-95; p.495.

Agnivesa.Charaka Samhita Vol I. Trans R K Sharma, Bhagwan Dash. Reprint ed. Varanasi: Chaukambha Sanskrit series office; 2011. Sutrasthana, Chapter 25. YajjapurusheeyamAdhyayam, sloka 40;p.427.

Susrutha. Illustrated Susruta Samhita Vol II. Trans Prof. KR Srikantha Murthy. Reprint ed. Varanasi: Chaukhambhaorientalia; 2012. Chikitsasthana. Chapter 38 Niruhakramachikitsitam; Sloka 55-59; p.373.

Vagbhata. Ashtanga Hridayam VolI. Trans T. Sreekumar. 5thed. Thrissur: Publication department Harisree hospital; 2007. Sutrasthana, Chapter 15. Shodhanadiganasangra haneeym Adhyayam, Sloka 9-10; p.324.

Agnivesa. Charaka Samhita Vol V. Trans R K Sharma, Bhagwan Dash. Reprint ed. Varanasi: Chaukambha Sanskrit series office; 2011. Chikitsasthana, Chapter 28. Vatavayadhichikitsa, sloka 96; p.49.

Vagbhata. Ashtanga Hridayam Vol II. Trans Prof. K R Srikantha Murthy. 9th ed. Varanasi: Chaukhambha Krishnadas Academy; 2012. Chikitsasthana, Chapter 21. Vatavayadhichikitsa, Sloka 17; p.500.

Amarasimha. Amarakosha. SastriHaragovind (ed.). Varanasi: Chaukambha Sanskrit Sansthan; 2012. p.203.

e-nighantu. Collection of Ayurvedic Lexicons. Madanadi Nighantu. Delhi: CCRAS; 2012. https://niimh.nic.in/ebooks/e-Nighantu/madanadinighantu.

Mahendra Bhogika. Dhanwantari Nighantu. Acharya Priyavrta Sharma(ed.). Varanasi: Chaukambha Publications; 2008.p.40.

Sodhala. Translated by Pandey G. Sodhala Nighantu. Varanasi: ChaukambhaKrishnadas Academy; 2009.p.32.

Madanapala. Translated by J L N Sastry. Madanapala Nighantu. Varanasi: Chaukambhaorientalia; 2010.p.47-48.

Kaiyyadeva. Translated by Sharma P V Sharma and G P Sharma. Kaiyyadeva Nighantu. Varanasi: Chaukambha Orientalia; 2013.p.12.

Pandit Narahari. Raja Nighantu. TripatiIndradeva(ed.). Varanasi: Chaukambha Krishnadas Academy; 2009.p.68.

Bhavamisra. Bhavaprakasha Nighantu. Dr K C Chunekar, G S Pandey (ed.). Varanasi: Chaukambha Bharati Academy; Reprint 2010.p.274-275.

Saraswathi Nighantu. S.D Kamat (ed). Delhi: Chaukambha Sanskrit Pratishthan; 2006. p.58.

Saligrama. Saligrama Nighantu Bhooshanam. Bombay: Khemaraj Srikrishnadas Prakashan; 2006. p.206-207.

Bapalal G Vaidya. Nighantu Adarsa. Vol 1. Varanasi: Chaukambha Bharati Academy; 2013. p. 444-445.

M.S. Krishnamurthy. Abhidhanamanjari of Bhishagarya. Varanasi: Chaukhambhaorientalia; 2012.p.13-25.

Aryadasa Kumara Singha. Mahaushadha Nighantu. Varanasi: Chaukambha Bharti Academy; 2006.p.105.

Priya Vrat Sharma. Priya Nighantu. Varanasi: Chaukambha Surbharati Prakashan; 2004.p.11.

Thayil Krishnan K. Ayurvedeeya Oshadhi Nighantu. Vol. 1 Thiruvananthapuram: Kerala Government Ayurvedic Publications; 2000. p.265-267.

Chikitsamanjari. SreemanNambootiri (ed). Kodungallor: Vidyarambham publications; 2008. Chapter Swarasadachikitsa; Sloka 2; p.159

Yogamrutam. SreemanNambootiri (ed). Alappuzha: Vidyarambham publishers; 1999. p. 91-92.

Sahasrayogam. K. V Krishnan Vaidyan, S. Gopala Pillai (ed). Alappuzha: Vidyarambham publishers; 2013. Chapter Swarasadachikitsa; p. 62.

Agnivesa. Charaka Samhita Vol I. Trans R K Sharma, Bhagwan Dash. Reprint ed. Varanasi:Chaukambha Sanskrit series office;2011.Sutrasthana, Chapter 4. Shadvirechanashatasriteeyam, sloka 9-17; p.89-99.

Susrutha. Illustrated Susruta Samhita Vol I. Trans Prof. KR Srikantha Murthy. Reprint ed. Varanasi: Choukambha Orientalia; 2012. Sutrasthana, Chapter 38. Dravyasangrahaneeyaadhyaya, Sloka 5-67; p.265-274.

Vagbhata. Ashtanga SangrahamVolI. Trans Prof. K R Srikantha Murthy. 9th ed. Varanasi: Chaukamba Orientalia; 2012. Sutrasthan, Chapter 18. Rasa bhediyaadhyaya, Sloka 19; p.340.

Vagbhata. Ashtanga SangrahamVolI. Trans Prof. K R Srikantha Murthy. 9th ed. Varanasi: Chaukamba Orientalia; 2012. Sutrasthana, Chapter 16. Vividha dravyaganasam grahaadhyaya, Sloka 3; p.310.

Vagbhata. Ashtanga SangrahamVolI. Trans Prof. K R Srikantha Murthy. 9th ed. Varanasi: Chaukamba Orientalia; 2012. Sutrasthana, Chapter 12. Dvividh oushadhavijnaneeyaadhyaya, Sloka 51; p.271.

Vagbhata. Ashtanga Sangraham VolI. Trans Prof. K R Srikantha Murthy. 9th ed. Varanasi: Chaukamba Orientalia; 2012. Sutrasthana, Chapter 15. Mahakashayasamgrahaadhyaya, Sloka 3-40; p.301-307.

Vagbhata. Ashtanga Hridayam Vol I. Trans T. Sreekumar. 5th ed. Thrissur: Publication department Harisree hospital; 2007. Sutrasthana, Chapter 10. Rasabhediyam, Sloka 22-24; p.237.

Vagbhata. Ashtanga Hridayam Vol I. Trans T. Sreekumar.5th ed. Thrissur: Publication department Harisree hospital; 2007. Sutrasthana, Chapter 6. Annaswaroopavijaneeyamadhyayam: Sloka 168;p.179.

P V Sharma. Namarupajnanam, Characterization of medicinal plants based on etymological derivation of names and synonyms. Varanasi: Satyapriyaprakashan; 2000. p.133-134.

Sabdakalpadrumam. Raja Radha Kanta Deva (ed). Varanasi: Chaukamha Sanskrit series; 2011.71.

Ministry of Health and Family welfare. Ayurveda Pharmacopoeia of India.1st edition. Government of India, Part 1. Vol 3.p.179-181.

Sharma P V. DravyagunaVijnana. Vol 2. Varanasi: Chaukhambha Bharati Academy; 2012.p.617-619.

Prakash L Hegde, Harini A. A textbook of DravyagunaVijnana. Vol 2. New Delhi: Chaukhambha publications; 2014. p. 102-108.

Agnivesa. Charaka SamhitaVol IV. Trans R K Sharma, BhagwanDash.Reprint ed. Varanasi: Chaukambha Sanskrit series office;2013.Chikitsa sthana, Chapter 26.Trimarmeeya Chikitsa, sloka 95;p.495.

Agnivesa. Charaka SamhitaVolIII. Trans R K Sharma, BhagwanDash.Reprint ed. Varanasi: Chaukambha Sanskrit series office; 2013. Chikitsa sthana, Chapter 14. ArshaChikitsa, sloka 200;p.622.

Susrutha. Illustrated Susruta Samhita Vol III. Trans Prof. KR Srikantha Murthy.Reprint ed. Varanasi: Chaukhambha orientalia; 2012. Utharasthana, Chapter 41.Shoshapratisheda, Sloka 32; p.255.

Susrutha. Illustrated Susruta Samhita Vol II. Trans Prof. KR Srikantha Murthy. Reprint ed. Varanasi: Chaukhambha orientalia; 2012. Chikitsasthana, Chapter 17. Visarpanadisthanarogachikitsa, Sloka 11;p.165.

Susrutha. IllustratedSusruta Samhita Vol II. Trans Prof. KR Srikantha Murthy.Reprint ed. Varanasi: Chaukhambha orientalia; 2012. Kalpasthana, Chapter 8. Kita kalpa, Sloka 102;p.494.

Vagbhata. Ashtanga Hridayam Vol II. Trans Prof. K R Srikantha Murthy.9th ed.Varanasi: Chaukhambha Krishnadas Academy; 2012. Chikitsa sthana, Chapter 7. Madatyayadi chikitsa, Sloka 33-34; p.291.

Vagbhata. Ashtanga Hridayam Vol II. Trans Prof. K R Srikantha Murthy.9th ed. Varanasi: Chaukhambha Krishnadas Academy; 2012.Chikitsa sthana, Chapter9. Atisara chikitsa, Sloka 13-14; p.336.

Vagbhata. Ashtanga Hridayam Vol II. Trans Prof. K R Srikantha Murthy.9th ed.Varanasi: Chaukhambha Krishnadas Academy; 2012.Chikitsa sthana. Chapter 9.Atisarachikitsa, Sloka 86;p.348.

Vagbhata. Ashtanga Hridayam Vol II. Trans Prof. K R Srikantha Murthy.9th ed.Varanasi: ChaukhambhaKrishnadas Academy; 2012.Chikitsa sthana. Chapter 22. Vatashonitachikitsa,Sloka9;p.514.

Bapalal Vaidya. Some Controversial Drugs in Indian Medicine. Varanasi: Chaukambha Orientalia; 2014.p226-228.

Kirthikar K R, Basu B D. Indian Medicinal Plants. Vol II. Dehradun: International book distributers; 2012. p. 758-760.

Council of Scientific & Industrial Research. The Wealth of India. New Delhi: Council of Scientific & Industrial Research; 2005.p. 232-234.

Ram P Rastogi, R N Mehrotra. Compendium of Indian Medicinal Plants. Lucknow: Central drug research institute; 2008. p.262-264.

Kolammal M, Aiyer Narayanan K. Pharmacognosy of Ayurvedic drugs of Travancore-cochin. Series 1, Number 2. Thiruvananthapuram: Department of Pharmacognosy, University of Travancore; 1992. p. 73-77.

Orient Logman. IndianMedicinal Plants. A Compendium of 500 species. Arya Vaidya Sala, Kottakkal; Volume 2. p.319-323.

V VSivarajan, Indira Balachandran. Ayurvedic Drugs and their Plant Sources. New Delhi: Oxford & IBH Publishing CO. PVT. LTD; Reprint2006. p.382-386.

William Dymock, C J H Warden, David Hooper. Pharmacographia indica- A history of the principal drugs of vegetable origin met within British India. Vol 1. Calcutta: Thacker Sping& Co.;1890. p. 507-509.

Purushottaman Kaushik, Anil Kumar Dhiman. Medicinal plants and raw drugs of India. Dehradun: Bishen Singh Mahendra Pal Singh; 2000. p.213-214.

J.S.Gamble. Flora of the Presidency of Madras.Vol1. Delhi: Neeraj Publishing House;Reprint 2016.p.345.

J.D.Hooker. The Flora of British India. Vol1. Delhi: Chaukhamba Publications;1875.p.161.

Atanu Bhattacharjee,ShastryChakrakodiShashidhara, SantanuSaha. Phytochemical and ethno-pharmacological profile of Desmodiumgangeticum (L.) DC.: A review.International Journal of biomedical research.2013;4(10):507-515.

A Niranjan and S K Tiwari. Phytochemical composition and antioxidant potential of Desmodiumgangeticum (Linn.) DC. Indian Journal of natural products and resources.2008;7(1):35-39.

Gino A Kurian, SrilalithaSuryanarayanan, Archana Raman, Jose Padikkala. Antioxidant effects of ethyl acetate extract of Desmodiumgangeticum root on myocardial ischemia reperfusion injury in rat hearts. Chinese medicine.2010;5(3):1-7.

Vandana Sankar, BalasubramaniamPangayarselvi, Ayyappan Prathapan,Kozhiparambil Gopalan Raghu. Desmodiumgangeticum (Linn.) DC. exhibits antihypertrophic effect in isoproterenol-induced cardiomyoblasts via amelioration of oxidative stress and mitochondrial alterations. Journal of cardiovascular pharmacology.2013;61(1):23-34.

Divya Hitler, Parthasarathy Arumugam, Mathivanan Narayanasamy, Elangovan Vellaichamya. Desmodiumgangeticum root extract attenuates isoproterenol-induced cardiac hypertrophic growth in rats. Journal of Pharmacy and Pharmacognosy Research.2014;2(5):129-137.

Rathi A, Rao CV, Ravishankar B, Deb S, Mehrotra S. Anti-inflammatory and anti-nociceptive activity of the water decoction Desmodiumgangeticum. Journal of Ethnopharmacology. 2004; 95:259-263.

Jain V, Prasad V, Pandey R. Wound healing activity of Desmodiumgangeticumin different wound models. Journal of Plant Sciences.2006; 1(3): 247–253.

Prasad MVV, Balakrishna K, Carey MW. Hepatoprotective activity of roots of Desmodiumgangeticum(Linn.) DC. Asian Journal of Chemistry.2005; 17(4): 2847-2849.

Hanumanthachar J, Milind P. Pharmacological evidences for the antiamnesic effects of Desmodiumgangeticumin mice. Iranian Journal of PharmaceuticalResearch.2010; 6(3):199–207.

Govindarajan R, Asare-Anane H, Persaud S, Jones P, Houghton PJ. Effect of Desmodiumgangeticumextract on blood glucose in rats and on insulin secretion in vitro. Planta Medica.2007; 73(2): 427–432.

Ayyavu M, Robert J, Dowlathabad MR, Devarajan T. Gastroprotective effect of Desmodiumgangeticum(Linn.) DC. roots on gastric ulcer mouse models. RevistaBrasileira de Farmacognosia.2012; 22(5): 37-44.

Bhavesh D. Vaghela, Sandip Budhadev, Leena Shukla. Pharmacological activities of Desmodiumgangeticum: An overview. Plant Science Monitor.2013; 4(4): 264-278.

Downloads

Published

2022-09-16