RELATIONSHIP BETWEEN OCULAR PRESSURES AND ABO BLOOD GROUPS IN ADULT YOGA PRACTITIONERS
Abstract
Background: Ocular perfusion pressure (OPP), a derivative of mean arterial pressure(MAP) and intra ocular pressure(IOP), is a dynamic biological parameter of ocular perfusion. It varies with varying Blood Pressure (BP) and IOP and determines the blood flow to the ocular tissues. Glaucoma is one of the most common causes of irreversible vision loss worldwide. Raised IOP and reduced OPP are the risk factors in the pathogenesis of glaucoma. It has been observed that Yoga has an impact on these ocular pressures. Studies carried out on different ethnic groups shows conflicting results regarding the association between glaucoma and ABO blood groups. This study was taken up since there is paucity of literature to establish the link between glaucoma and blood groups in yoga practitioners.
Objectives: To evaluate the association of IOP and OPP values with ABO blood types in yoga practitioners.
Materials and Methods: 70 adult yoga practitioners in the age group of 18 to 25 years were recruited. Institutional ethical clearance was obtained and written informed consent was taken. Blood groups of the subjects were determined by ABO typing. IOP and BP were recorded using rebound tonometer and sphygmomanometer respectively. OPP was calculated using the formula, OPP = (2/3) mean arterial pressure - IOP.
Results: There was no significant association between ABO blood groups and MAP, IOP and OPP values.
Conclusion: This study aimed at comprehending the effects of risk factors of glaucoma and ABO blood groups in yoga practitioners and it revealed the lack of association between them. This could probably be due to genetic variations in the race and ethnicity.
Key words: ABO Blood groups, Intra ocular pressure, Ocular perfusion pressure.
References
Kingman S. Glaucoma is second leading cause of blindness globally. Bull World Health Organ 2004;82:887-8.
McMonnies CW. Glaucoma history and risk factors. J Optom. 2017;10(2):71–8.
Machiele R, Motlagh M, Patel BC. Intraocular Pressure. StatPearls Publishing Treasure Island (FL); 2019. https://www.ncbi.nlm.nih.gov/books/NBK532237
Sudha BS and Vinitha KR. A comparative study of ocular pressure changes in yogic practitioners and non- practitioners of yoga. International Journal of AYUSH 2021;10(5):86-92.
Dada T, Mittal D, Mohanty K. Mindfulness Meditation Reduces Intraocular Pressure, Lowers Stress Biomarkers and Modulates Gene Expression in Glaucoma: A Randomized Controlled Trial. J glaucoma 2018; 27(12):1061-67.
Anne MVB, Gillies WE. Blood groups as genetic markers in glaucoma. British Journal of Ophthalmology 1988; 72: 270-3.
Lindén S, Mahdavi J, Semino-Mora CS, et al. Role of ABO secretor status in mucosal innate immunity and H. pylori infection. PLoS Pathog 2008; 4:e2.
Wazirali H, Ashfaque RA, Herzig JW. Association of blood group A with increased risk of coronary heart disease in the Pakistani population. Pak J Physiol 2005;1:1–2.
Khan MI, Shazia M, Farah A, Akhtar N, Asifa A, Raheel Q. Association of ABO blood groups with glaucoma in the Pakistani population. Can J Ophthalmol 2009;44(5):582–6.
Robert NW, James DB, David GH, Felipe M. Intraocular pressure Consensus, series 4.
Kugler publications; Netherlands:2007.
Leske MC, Nemesure BB, He Q, Mendell N, Polednak A. Open-angle glaucoma and blood groups. The Barbados Eye Study. Arch Ophthalmol. 1996 Feb; 114(2):205-10.
Garg MP, Pahwa JM. Primary glaucoma and blood groups. Indian journal of ophthalmology. 1965; 13(4): 127-9.
Jeddi Blouza A, Loukil I, Mhenni A, Ben Rayana C, Hmida S. Blood groups and open-angle glaucoma in Tunisia. J Fr Ophtalmol 2007; 30:493–6.
Blika S, Ringvold A, Braathen LN, Juel E. ABO-blood groups and D-antigen in simple and capsular glaucoma. Acta Ophthalmol (Copenh). 1984 Dec; 62(6):1009- 13.
David R and Jenkins T. Genetic markers in glaucoma. British Journal of ophthalmology.1980; 64:227-31.
Zaree R, Eslami Y, Fakhraie G, Ghannadi F, Varmazyar R. Association between glaucoma and blood groups. Acta Medica Iranica 2006; 44:329–32.
