HPTLC FINGER PRINTING PROFILE OF ELEPHANTOPUS SCABER LINN.
Abstract
Elephantopus scaber Linn. is an important medicinal plant which is used to treat various diseases such as as melancholia, epilepsy, skin diseases, conjunctivitis, mouth ulcers, wounds, dysuria and dysentery. The whole plant is a good source of various bioactive phytochemicals which are responsible for various pharmacological activities such asanti-inflammatory, wound healing, anti-oxidant, diuretic, anti-ulcer, hepato protective, anti-viral, anti-bacterial, memory boosting , anti- anxiety etc. The High Performance Thin Layer Chromatography was carried out in chloroform, methanol and water extract of Elephantopus scaber Linn. HPTLC analysis was performed using Toluene: ethyl acetate: formic acid [6: 5: 1 v/v/v] as a mobile phase. HPTLC plate was scanned at 254nm and 366 nm after derivatization showing good partition and banding. Comparisons showed that maximum numbers of chemical constituents were obtained for the methanol extract followed by chloroform and water extracts. Peaks with similar Rf value obtained in various extracts are indicative of similar compounds. But the area of the peaks may differ which shows the difference in affinity of a particular chemical constituent to a solvent.
KEY WORDS: Elephantopus scaber Linn, HPTLC finger printing profile
References
Van Rheede. Hortus malabaricus. K S Manilal (ed.).Vol. 10.Thiruvanthapuram: Publication division of Kerala University; 2000. p25–27.
Yogamrtham. Trans. Sreeman Nampoothiri. 3rd ed. Alappuzha: Vidhyarambham publications; 2004.p312.
Sachin M Hiradev, Vinod D Rangari. Elephantopus scaber Linn: A review on its ethnomedical, phytochemical and pharmacological profile. J Appl Biomed2014; 49–61. Available from:ab.zsf.jcu.cz/artkey/jab-201402-0001_elephantopus-scaber-linn-a-review-on-its-ethnomedical-phytochemical-and-pharmacological-profile.php
Herbs from the distant lands. Elephantopus scaber, Elephantopus mollis, Elephantopus tomentosus-Elephant foot. Available from: http://herbs from the distant lands.blogspot.com/2016/07?m=1.[ Accessed 2 January 2021]
Farha Arakkaveettil Kabeer, Remani Prathapan. Phyto-pharmacological profile of Elephantopus scaber Linn.Pharmacologia2014; 5(8):272–285.
