Kaempferia rotunda Linn.:- EVALUATION OF IN VITRO THROMBOLYTIC ACTIVITY
Abstract
Chengazhuneerkizhangu, botanically identified as Kaempferia rotunda Linn. is a drug widely used in folklore practice in Kerala, India. The drug even though widely used within the state its medicinal potential is still unknown to a large scientific community. In the present time, with the increase in global demand of herbal medicine and alarming depletion of traditional medicinal plants it is needed to explore the potential of folklore medicines. Kaempferia rotunda Linn is evaluated as part of the study to validate its folklore claim. It was subjected to in vitro analysis to evaluate its thrombolytic activity. The drug was used in its aqueous extract form in three different concentrations 2mg/ml, 4mg/ ml and 6 mg/ml and distilled water was taken as the control. On statistical analysis significant thrombolytic activity was exhibited by the drug in the concentrations 4mg/ml and 6 mg/ml (p<0.0001).
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