THERAPEUTIC EVALUATION OF A TOPICAL UNANI FORMULATION IN PATIENTS WITH QŪBĀ (DERMATOPHYTOSIS): A CASE SERIES

Aaliya Ansari, Qamar Uddin, Munawwar Husain Kazmi, Dr. Arzeena Jabeen

Abstract


Introduction

Qūbā (Dermatophytosis/ Ringworm) is a superficial chronic fungal infection of the skin caused by dermatophytes. It is a common cause of skin disease worldwide, especially in tropical areas. The three main genera of dermatophyte fungi that affect humans are Trichophyton, Microsporum and Epidermophyton. Tinea corporis occurs on the trunk and extremities, and usually presents with typical annular or circular lesions, vesicular or scaly, itchy papules with erythematous border and central clearing, and sometimes oozing. The diagnosis is confirmed by microscopy of skin scrapings using 10% KOH preparation or by fungal culture.

Methodology/ Case Presentation

We had four cases of Qūbā (Dermatophytosis), presenting with itching, erythema, scaling, and central clearing with peripheral raised margins of the glabrous skin. KOH mount examination of skin scraping, and haematological & biochemical investigations were performed before and after treatment. Marham Kharish Jadeed was topically applied on the skin lesions for a period of 29 to 51 days.

Discussion

After 29 to 51 days of topical application of Marham Kharish Jadeed, the symptoms and signs of Qūbā (Dermatophytosis) were subsided, and KOH mount examination became negative revealing the efficacy of the study drug. All the patients were having values of their haematological and biochemical investigations within normal limits after treatment, showing the safety of the study drug.

Conclusion

The local application of Marham Kharish Jadeed was found effective in Dermatophytosis, suggesting its antifungal activity. No adverse effects were seen during study, and no recurrence of the lesions was observed after treatment. However, further study with larger series and longer follow-up is required.

KEYWORDS: Dermatophytosis, Qūbā, Marham Kharish Jadeed, KOH mount

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