STANDARDISATION OF KUVALAYAGHRTA: A POTENTIAL NOOTROPIC SUPPLEMENT

VijayaLekshmi R, M.A. Shajahan, Indulekha V C

Abstract


Nootropics are groups of medicines which are known to act as memory enhancers.There is a growing need for such medicines from alternate systems of medicine to prevent or delay memory loss and related disorders.Classical textbooks in Ayurveda describe a group called as MedhyaRasayana, which act as neuro-nutrients.ChathushkuvalayaRasayana is one such ghee preparation mentioned in Ashtangahrdaya.In it, Kuvalaya, botanically identified in Kerala as Monochoria vaginalisPresl.is the only herbal ingredient.Though Kuvalaya has been considered widely as a memory enhancer, there is scarce published literature regarding standardisation aspects of Kuvalayaghrta.In this work, we first phytochemically standardized the ingredients of Kuvalayaghrtaincluding its Atomic Absorption spectroscopy,Thin Layer Chromatography(TLC) and High Performance Thin Layer Chromatography(HPTLC) profiling followed by the preparation of the ghrta(ghee) according to the standard procedurementioned in Ayurvedic Formulary of India.Kuvalayaghrta was also standardised
physicochemically and was found to be safe for internal administration.All the observations obtained in this study can be used for future reference.
Keywords: ChathushkuvalayaRasayana, KuvalayaGhrta, Monochoria vaginalis Presl.,MedhyaRasayana, Thin Layer Chromatography.


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ACKNOWLEDGMENT

Dr. M. A Shajahan, Professor (Retd.), Department of DravyagunaVijnanam, Government

Ayurveda College,Thiruvananthapuram, Kerala-695001, India.

Dr.Indulekha V.C, Asst. Professor, Department of DravyagunaVijnanam, Government Ayurveda College,Thiruvananthapuram, Kerala-695001, India.

CONFLICT OF INTEREST

Nil

ABBREVIATION

AAS - Atomic Absorption spectroscopy

AFI – Ayurvedic Formulary of India

AGMARK – Agricultural Marketing

API – Ayurvedic Pharmacopoeia of India

EMEA – European Medicine Agency

HPTLC - High Performance Thin Layer Chromatography

ICH – International Conference on Harmonisation

KG – KuvalayaGhrta

Rf – Retardation factor

TLC - Thin Layer Chromatography

UV – Ultra Violet


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